KB-0742 dihydrochloride
Cat. No.:YN290720
CAS No. :2416874-75-2
产品名称: | KB-0742 dihydrochloride |
CAS No.: | 2416874-75-2 |
Chemical Name: | |
Synonyms: | KB-0742 dihydrochloride |
分子量: | 360.33 |
分子式: | C16H25N5.2ClH |
SMILES: | Cl.Cl.CCC(CC)C1=NC2=CC=N[N]2C(=C1)NC3CCC(N)C3 |
存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
运输: | Room temperature in continental US; may vary elsewhere. |
产品描述: | KB-0742 dihydrochloride 是一种有效的,选择性的和具有口服活性的CDK9抑制剂,对CDK9/cyclin T1的IC50为 6 nM。KB-0742 dihydrochloride 对CDK9/cyclin T1具有选择性,其选择性是其他CDK激酶的 50 倍以上。KB-0742 dihydrochloride 具有有效的抗肿瘤活性。 |
IC50和靶点: | [{name:"CDK9/cyclinT1:6 nM (IC50)"}] |
In Vitro: | |
In Vivo: | |
Clinical Trial: | |
Solvent & Solubility: |