Camonsertib
Cat. No.:YN290722
产品名称: | Camonsertib |
CAS No.: | 2417489-10-0 |
Chemical Name: | |
Synonyms: | RP-3500; ATR inhibitor 4 |
分子量: | 410.47 |
分子式: | C21H26N6O3 |
SMILES: | 暂无 |
存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
运输: | Room temperature in continental US; may vary elsewhere. |
产品描述: | Camonsertib (RP-3500) 是一种口服有效的,选择性ATR激酶抑制剂 (ATRi),在生化试验中的IC50为 1.00 nM。Camonsertib 对ATR的选择性是mTOR的 30 倍 (IC50=120 nM),是 ATM、DNA-PK 和PI3Kα激酶的 > 2,000 倍。Camonsertib 具有有效的抗肿瘤活性。 |
IC50和靶点: | |
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In Vivo: | |
Clinical Trial: | |
Solvent & Solubility: |