Dot1L-IN-4
Cat. No.：YN310499
CAS No. ：2565705-02-2
| 产品名称: | Dot1L-IN-4 |
| CAS No.: | 2565705-02-2 |
| Chemical Name: | N1-[(S)-(3-chloro-2-pyridinyl)(2,2-difluoro-1,3-benzodioxol-4-yl)methyl]-N2-[4-methoxy-6-(1-piperazinyl)-1,3,5-triazin-2-yl]-4-(methylsulfonyl)-1,2-benzenediamine |
| Synonyms: | |
| 分子量: | 661.0804064 |
| 分子式: | C28H27ClF2N8O5S |
| SMILES: | COC1=NC(N2CCNCC2)=NC(NC(C=C(C=C3)S(C)(=O)=O)=C3N[C@H](C4=C(C=CC=N4)Cl)C5=C6C(OC(F)(O6)F)=CC=C5)=N1 |
| 存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
| 运输: | Room temperature in continental US; may vary elsewhere. |
| 产品描述: | Dot1L-IN-4 是一种有效的类端粒沉默干扰体 1 (DOT1L) 抑制剂，IC50 SPADOT1L为 0.11 nM。 |
| IC50和靶点: | [{name:"DOT1L:0.11 nM (IC50)"}] |
| In Vitro: | |
| In Vivo: | |
| Clinical Trial: | |
| Solvent & Solubility: |
Stauffer, F., Weiss, A., Scheufler, C., et al.New potent DOT1L inhibitors for in vivo evaluation in mouseACS Med. Chem. Lett.10(12),1655-1660(2019)
