BML-259
Cat. No.:YN290734
CAS No. :267654-00-2
产品名称: | BML-259 |
CAS No.: | 267654-00-2 |
Chemical Name: | N-[5-(1-methylethyl)2-thiazolyl]-benzeneacetamide |
Synonyms: | |
分子量: | 260.4 |
分子式: | C14H16N2OS |
SMILES: | O=C(Cc1ccccc1)Nc1ncc(s1)C(C)C |
存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
运输: | Room temperature in continental US; may vary elsewhere. |
产品描述: | BML-259 是一种有效的细胞周期蛋白依赖性激酶 5(Cdk5)抑制剂,对Cdk5和Cdk2的 IC50分别为 64 和 98 nM。 |
IC50和靶点: | |
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Clinical Trial: | |
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Helal, C.J., Sanner, M.A., Cooper, C.B., et al.Discovery and SAR of 2-aminothiazole inhibitors of cyclin-dependent kinase 5/p25 as a potential treatment for Alzheimer's diseaseBioorg. Med. Chem. Lett.14,5521-5525(2004)