TN-16
Cat. No.：YN290754
| 产品名称: | TN-16 |
| CAS No.: | 33016-12-5 |
| Chemical Name: | 3-[1-(phenylamino)ethylidene]-5-(phenylmethyl)-2,4-pyrrolidinedione |
| Synonyms: | |
| 分子量: | 306.4 |
| 分子式: | C19H18N2O2 |
| SMILES: | O=C(/C1=C(C)\NC2=CC=CC=C2)NC(CC3=CC=CC=C3)C1=O |
| 存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
| 运输: | Room temperature in continental US; may vary elsewhere. |
| 产品描述: | TN-16 是一种有效的微管聚合抑制剂，IC50为 0.4-1.7 µM。 |
| IC50和靶点: | |
| In Vitro: | |
| In Vivo: | |
| Clinical Trial: | |
| Solvent & Solubility: |
Arai, T.Inhibition of microtubule assembly in vitro by TN-16, a synthetic antitumor drugFEBS Lett.155(2),273-276(1983)
Roach, M.C., and Luduena, R.F.The effect of TN-16 on the alkylation of tubulinBiochem. Biophys. Res. Commun.129(1),200-205(1985)
Nakamura, M., Kanda, S., Kawamura, M., et al.Effects of low concentration of vinblastine on the anchorage-independent growth and in vitro invasion of human renal carcinoma cell linesCancer Lett.69(2),85-91(1993)
Liskovykh, M., Lee, N.C.O., Larinov, V., et al.Moving toward a higher efficiency of microcell-mediated chromosome transferMol. Ther. Methods Clin. Dev.3,16043(2016)
