Aurora kinase inhibitor-2
Cat. No.：YN290756
| 产品名称: | Aurora kinase inhibitor-2 |
| CAS No.: | 331770-21-9 |
| Chemical Name: | N-[4-[(6,7-dimethoxy-4-quinazolinyl)amino]phenyl]-benzamide |
| Synonyms: | |
| 分子量: | 400.4 |
| 分子式: | C23H20N4O3 |
| SMILES: | COC1=C(OC)C=C(C(NC2=CC=C(NC(C3=CC=CC=C3)=O)C=C2)=NC=N4)C4=C1 |
| 存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
| 运输: | Room temperature in continental US; may vary elsewhere. |
| 产品描述: | Aurora kinaseinhibitor-2 是一种选择性和 ATP 竞争性的 Aurora 激酶抑制剂，对Aurora A和Aurora B的IC50分别为 310 nM 和 240 nM。 |
| IC50和靶点: | [{name:"Aurora A:310 nM (IC50)"},{name: "Aurora B:240 nM (IC50)"}] |
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| Clinical Trial: | |
| Solvent & Solubility: |
Heron, N.M., Anderson, M., Blowers, D.P., et al.SAR and inhibitor complex structure determination of a novel class of potent and specific Aurora kinase inhibitorsBioorg. Med. Chem. Lett.16(5),1320-1323(2006)
