3′-Deoxyguanosine
Cat. No.：YN290763
CAS No. ：3608-58-0
| 产品名称: | 3′-Deoxyguanosine |
| CAS No.: | 3608-58-0 |
| Chemical Name: | 3'-deoxy-guanosine |
| Synonyms: | Guanosine, 3'-deoxy- |
| 分子量: | 267.2 |
| 分子式: | C10H13N5O4 |
| SMILES: | O=C1C2=C(N([C@H]3[C@H](O)C[C@@H](CO)O3)C=N2)N=C(N)N1 |
| 存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
| 运输: | Room temperature in continental US; may vary elsewhere. |
| 产品描述: | 3′-Deoxyguanosine (Guanosine, 3'-deoxy-) 是一种嘌呤核苷类似物。嘌呤核苷类似物具有广泛的抗肿瘤活性，靶向惰性淋巴系统恶性肿瘤。这一过程中的抗癌机制依赖于抑制 DNA 合成，诱导细胞凋亡 (apoptosis) 等。 |
| IC50和靶点: | |
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Canduri, F., Silva, R.G., dos Santos, D.M., et al.Structure of human PNP complexed with ligandsActa Crystallogr. D Biol. Crystallogr.61(Pt 7),856-862(2005)
Traversa, U., Bombi, G., Camaioni, E., et al.Rat brain guanosine binding site. Biological studies and pseudo-receptor constructionBioorg. Med. Chem.11(24),5417-5425(2003)
King, R.W., Zecher, M., and Jefferies, M.W.Inhibition of the replication of a hepatitis C virus-like RNA template by interferon and 3'-deoxycytidineAntivir. Chem. Chemother.13(6),363-370(2002)
