MST-312
Cat. No.：YN290765
CAS No. ：368449-04-1
| 产品名称: | MST-312 |
| CAS No.: | 368449-04-1 |
| Chemical Name: | N,N'-1,3-phenylenebis[2,3-dihydroxy-benzamide |
| Synonyms: | Telomerase Inhibitor IX |
| 分子量: | 380.35092 |
| 分子式: | C20H16N2O6 |
| SMILES: | OC1=C(O)C(C(NC2=CC=CC(NC(C3=C(O)C(O)=CC=C3)=O)=C2)=O)=CC=C1 |
| 存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
| 运输: | Room temperature in continental US; may vary elsewhere. |
| 产品描述: | MST-312 是一个telomerase抑制剂。MST-312 是绿茶表没食子儿茶素没食子酸酯 (EGCG) 的化学修饰衍生物。MST-312 可用于肿瘤的研究，如多发性骨髓瘤 (MM)。 |
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Seimiya, H., Oh-hara, T., Suzuki, T., et al.Telomere shortening and growth inhibition of human cancer cells by novel synthetic telomerase inhibitors MST-312, MST-295, and MST-1991Mol. Cancer Ther.1(9),657-665(2002)
Wong, V.C.H., Morrison, A., Tabori, U., et al.Telomerase inhibition as a novel therapy for pediatric ependymomaBrain Pathol.20(4),780-786(2010)
Serrano, D., Bleau, A.-M., Fernandez-Garcia, I., et al.Inhibition of telomerase activity preferentially targets aldehyde dehydrogenase-positive cancer stem-like cells in lung cancerMol. Cancer10(96),(2011)
Haberichter, J., Roberts, S., Abbasi, I., et al.The telomerase inhibitor MST-312 interferes with multiple steps in the herpes simplex virus life cycleJ. Virol.89(19),9804-9816(2015)
