SW155246
Cat. No.:YN310511
CAS No. :420092-79-1
产品名称: | SW155246 |
CAS No.: | 420092-79-1 |
Chemical Name: | 4-chloro-N-(4-hydroxy-1-naphthalenyl)-3-nitro-benzenesulfonamide |
Synonyms: | |
分子量: | 378.8 |
分子式: | C16H11ClN2O5S |
SMILES: | ClC1=CC=C(S(NC2=CC=C(O)C3=C2C=CC=C3)(=O)=O)C=C1[N+]([O-])=O |
存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
运输: | Room temperature in continental US; may vary elsewhere. |
产品描述: | SW155246 is aDNA methyltransferase(DNMT1) selective inhibitor withIC50s of 1.2 and 38 μM for hDNMT1 and mDNMT3A, respectively. SW155246 can be used for the research ofcancerandother diseases. |
IC50和靶点: | |
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In Vivo: | |
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Solvent & Solubility: |
Kilgore, J.A., Du, X., Melito, L., et al.Identification of DNMT1 selective antagonists using a novel scintillation proximity assayJ. Biol. Chem.288(27),19673-19684(2013)