6-Chloropurine Riboside
Cat. No.：YN290785
| 产品名称: | 6-Chloropurine Riboside |
| CAS No.: | 5399-87-1 |
| Chemical Name: | 6-chloro-9-β-D-ribofuranosyl-9H-purine |
| Synonyms: | 6-Chloropurine riboside |
| 分子量: | 286.6716 |
| 分子式: | C10H11ClN4O4 |
| SMILES: | ClC1=C(N=CN2[C@]3([H])O[C@H](CO)[C@@H](O)[C@H]3O)C2=NC=N1 |
| 存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
| 运输: | Room temperature in continental US; may vary elsewhere. |
| 产品描述: | Chloropurine riboside 是一种嘌呤核苷类似物。嘌呤核苷类似物具有广泛的抗肿瘤活性，靶向惰性淋巴系统恶性肿瘤。这一过程中的抗癌机制依赖于抑制 DNA 合成，诱导细胞凋亡 (apoptosis) 等。 |
| IC50和靶点: | |
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Dolezal, K., Popa, I., Hauserová, E., et al.Preparation, biological activity and endogenous occurrence of N6-benzyladenosinesBioorg. Med. Chem.15(11),3737-3747(2007)
Kim, Y.A., Sharon, A., Chu, C.K., et al.Synthesis, biological evaluation and molecular modeling studies of N6-benzyladenosine analogues as potential anti-toxoplasma agentsBiochem. Pharmacol.73(10),1558-1572(2007)
