3-(4-Pyridyl)indole
Cat. No.：YN290805
| 产品名称: | 3-(4-Pyridyl)indole |
| CAS No.: | 7272-84-6 |
| Chemical Name: | 3-(4-pyridinyl)-1H-indole |
| Synonyms: | Rockout; 3-(4-Pyridinyl |
| 分子量: | 194.2 |
| 分子式: | C13H10N2 |
| SMILES: | C12=CC=CC=C1NC=C2C3=CC=NC=C3 |
| 存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
| 运输: | Room temperature in continental US; may vary elsewhere. |
| 产品描述: | 3-(4-Pyridyl)indole (Rockout) 是一种 Rho 激酶 (ROCK) 抑制剂，IC50值为 25 μM。在伤口愈合试验中，3-(4-Pyridyl)indole 可以抑制起泡并导致肌动蛋白应力纤维溶解。 |
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Olson, M.F.Applications for ROCK kinase inhibitionCurr. Opin. Cell Biol.20(2),242-248(2008)
Narumiya, S., Tanji, M., and Ishizaki, T.Rho signaling, ROCK and mDia1, in transformation, metastasis and invasionCancer Metastasis Rev.28(1-2),65-76(2009)
Watanabe, K., Ueno, M., Kamiya, D., et al.A ROCK inhibitor permits survival of dissociated human embryonic stem cellsNat. Biotechnol.25(6),681-686(2007)
Yarrow, J.C., Totsukawa, G., Charras, G.T., et al.Screening for cell migration inhibitors via automated microscopy reveals a Rho-kinase inhibitorChem. Biol.12(3),385-395(2005)
