10-Nitrolinoleic acid
Cat. No.：YN290810
| 产品名称: | 10-Nitrolinoleic acid |
| CAS No.: | 774603-04-2 |
| Chemical Name: | 10-nitro-9E,12Z-octadecadienoic acid |
| Synonyms: | |
| 分子量: | 325.4 |
| 分子式: | C18H31NO4 |
| SMILES: | CCCCC/C=C\C/C([N+]([O-])=O)=C\CCCCCCCC(O)=O |
| 存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
| 运输: | Room temperature in continental US; may vary elsewhere. |
| 产品描述: | 10-Nitrolinoleic acid 是一种有效的过氧化物酶体增殖物激活受体 γ (PPARγ) 激动剂。10-Nitrolinoleic acid 与 [3H]Rosiglitazone 竞争性结合 PPAR-γ，IC50值为 0.22 μM。 |
| IC50和靶点: | [{name:"PPARγ:0.22 μM (IC50)"}] |
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Dunny, E., and Evans, P.Stereocontrolled synthesis of the PPAR-γ agonist 10-nitrolinoleic acidJ. Org. Chem.75(15),5334-5336(2010)
Woodcock, S.R., Salvatore, S.R., Bonacci, G., et al.Biomimetic nitration of conjugated linoleic acid: Formation and characterization of naturally occurring conjugated nitrodienesJ. Org. Chem.79(1),25-33(2014)
