SMTIN-T140
Cat. No.：YN310525
| 产品名称: | SMTIN-T140 |
| CAS No.: | 849727-81-7 |
| Chemical Name: | 5-[3-[4-[2-(4-fluorophenyl)ethoxy]phenyl]propyl]-2-furancarboxylic acid |
| Synonyms: | |
| 分子量: | 368.4 |
| 分子式: | C22H21FO4 |
| SMILES: | FC1=CC=C(CCOC2=CC=C(CCCC3=CC=C(C(O)=O)O3)C=C2)C=C1 |
| 存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
| 运输: | Room temperature in continental US; may vary elsewhere. |
| 产品描述: | D942 是一种可透过细胞的AMPK激动剂，部分抑制线粒体复合物 I。在多发性骨髓瘤细胞中，D942 抑制细胞生长。 |
| IC50和靶点: | |
| In Vitro: | |
| In Vivo: | |
| Clinical Trial: | |
| Solvent & Solubility: |
Kosaka, T., Okuyama, R., Sun, W., et al.Identification of molecular target of AMP-activated protein kinase activator by affinity purification and mass spectrometryAnal. Chem.77(7),2050-2055(2005)
Baumann, P., Mandl-Weber, S., Emmerich, B., et al.Activation of adenosine monophosphate activated protein kinase inhibits growth of multiple myeloma cellsExp. Cell Res.313(16),3592-3603(2007)
Roca, H., Varsos, Z.S., and Pienta, K.J.CCL2 is a negative regulator of AMP-activated protein kinase to sustain mTOR complex-1 activation, survivin expression, and cell survival in human prostate cancer PC3 cellsNeoplasia11(12),1309-1317(2009)
