GQ-16
Cat. No.：YN290824
CAS No. ：870554-67-9
| 产品名称: | GQ-16 |
| CAS No.: | 870554-67-9 |
| Chemical Name: | 5Z-[(5-bromo-2-methoxyphenyl)methylene]-3-[(4-methylphenyl)methyl]-2,4-thiazolidinedione |
| Synonyms: | GQ-16; GQ 16; GQ16 |
| 分子量: | 418.3 |
| 分子式: | C19H16BrNO3S |
| SMILES: | BrC1=CC(/C=C2C(N(CC3=CC=C(C)C=C3)C(S/2)=O)=O)=C(OC)C=C1 |
| 存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
| 运输: | Room temperature in continental US; may vary elsewhere. |
| 产品描述: | GQ-16 是PPARγ的中等亲和力配体，Ki值为 160 nM。GQ-16 有效抑制Cdk5介导的PPARγ磷酸化。GQ-16 也是PPARγ的部分激动剂，可减少脂肪生成。GQ-16 促进胰岛素增敏作用而不会增加体重。 |
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Amato, A.A., Rajagopalan, S., Lin, J.Z., et al.GQ-16, a novel PPARγ ligand, promotes insulin sensitization without weight gainJ. Biol. Chem.287(33),28169-28179(2012)
