DTHIB
Cat. No.:YN290829
CAS No. :897326-30-6
产品名称: | DTHIB |
CAS No.: | 897326-30-6 |
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分子量: | 309.68 |
分子式: | C13H9ClFN3O3 |
SMILES: | [O-][N+](=O)C1=CC(=CC=C1Cl)NC(=O)NC2=CC=C(F)C=C2 |
存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
运输: | Room temperature in continental US; may vary elsewhere. |
产品描述: | DTHIB 是一种直接和选择性的heat shock factor 1 (HSF1)抑制剂,DTHIB 与HSF1DNA 结合域结合的Kd为 160 nM。DTHIB 抑制HSF1癌症基因标记 (HSF1 CaSig),并选择性刺激核HSF1的降解。DTHIB 具有有效的抗癌活性,可用于前列腺癌的研究。 |
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