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Tubulysin IM-3

Cat. No.:YN290841

  • CAS No. :94608-23-8

    • 产品资料
    • 生物活性
    • 参考文献
    • 产品名称: Tubulysin IM-3
      CAS No.: 94608-23-8
      Chemical Name: 1,3-dimethoxy-5-[(1Z)-2-(4-methoxyphenyl)ethenyl]-benzene
      Synonyms:
      分子量:270.3
      分子式:C17H18O3
      SMILES:COC1=CC(/C=C\C2=CC=C(OC)C=C2)=CC(OC)=C1
      存储:Please store the product under the recommended conditions in theCertificate of Analysis.
      运输:Room temperature in continental US; may vary elsewhere.
      Select Batch:
      Purity: 98%
    • 产品描述: Cis-trismethoxy resveratrol 是一种有效的抗有丝分裂活性物,抑制微管蛋白聚合,IC50值为 4 μM。
      IC50和靶点:
      In Vitro:
      In Vivo:
      Clinical Trial:
      Solvent & Solubility:
    • Borra, M.T., Smith, B.C., and Denu, J.M.Mechanism of human SIRT1 activation by resveratrolJ. Biol. Chem.280(17),17187-17195(2005)

      Howitz, K.T., Bitterman, K.J., Cohen, H.Y., et al.Small molecule activators of sirtuins extend Saccharomyces cerevisiae lifespanNature425,191-196(2003)

      Schneider, Y., Chabert, P., Stutzmann, J., et al.Resveratrol analog (Z)-3,5,4'-trimethoxystilbene is a potent anti-mitotic drug inhibiting tubulin polymerizationInt. J. Cancer107,189-196(2003)

      Cushman, M., Nagarathnam, D., Gopal, D., et al.Synthesis and evaluation of stilbene and dihydrostilbene derivatives as potential anticancer agents that inhibit tubulin polymerizationJ. Med. Chem.34,2579-2588(1991)

      Lin, H.S., and Ho, P.C.A rapid HPLC method for the quantification of 3,5,4'-trimethoxy-trans-stilbene (TMS) in rat plasma and its application in pharmacokinetic studyJ. Pharm. Biomed. Anal.49,387-392(2009)

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    Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

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    质量 浓度 体积 分子量
    稀释计算器 :
    Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)
    • C1
      V1
      C2
      V2
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