CDK/HDAC-IN-2
Cat. No.：YN310532
| 产品名称: | CDK/HDAC-IN-2 |
| CAS No.: | 96017-59-3 |
| Chemical Name: | 2-(2-propyn-1-yl)-octanoic acid |
| Synonyms: | |
| 分子量: | 182.3 |
| 分子式: | C11H18O2 |
| SMILES: | C#CCC(C(O)=O)CCCCCC |
| 存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
| 运输: | Room temperature in continental US; may vary elsewhere. |
| 产品描述: | 2-Hexyl-4-pentynoic acid ((±)-2-Hexyl-4-pentynoic acid)，丙戊酸 (VPA) 衍生物，具有抑制HDAC(IC50=13 µM) 和诱导HSP70的作用。具有强大的神经保护作用。2-Hexyl-4-pentynoic acid 在培养的神经元中引起组蛋白高度乙酰化并防止谷氨酸诱导的兴奋性毒性。 |
| IC50和靶点: | |
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| Solvent & Solubility: |
Leng, Y., Marinova, Z., Reis-Fernandes, M.A., et al.Potent neuroprotective effects of novel structural derivatives of valproic acid: Potential roles of HDAC inhibition and HSP70 inductionNeurosci. Lett.476(3),127-132(2010)
