Sovesudil
Cat. No.:YN290850
产品名称: | Sovesudil |
CAS No.: | 1333400-14-8 |
Chemical Name: | |
Synonyms: | PHP-201; AMA0076 |
分子量: | 407.44 |
分子式: | C23H22FN3O3 |
SMILES: | O=C(C1=CC(C2=CC(C(NC3=C(F)C=NC=C3)=O)=CC=C2CN)=CC=C1)OCCC |
存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
运输: | Room temperature in continental US; may vary elsewhere. |
产品描述: | Sovesudil (PHP-201) 是一种有效的、ATP 竞争性局部作用 Rho激酶(ROCK)抑制剂,对ROCKI 和ROCKII 的IC50分别为 3.7 和 2.3 nM。Sovesudil 降低眼压而不引起充血。 |
IC50和靶点: | [{name:"ROCK-I:3.7 nM (IC50)"},{name: "ROCK-II:2.3 nM (IC50)"}] |
In Vitro: | |
In Vivo: | |
Clinical Trial: | |
Solvent & Solubility: |