TAS-119
Cat. No.：YN290851
CAS No. ：1453099-83-6
| 产品名称: | TAS-119 |
| CAS No.: | 1453099-83-6 |
| Chemical Name: | |
| Synonyms: | TAS-119 |
| 分子量: | 506.36 |
| 分子式: | C23H22Cl2FN5O3 |
| SMILES: | N1(CCC(C(=O)O)(CC2C=CC(F)=C(NC3=NNC(C)=C3)N=2)CC1)C(C1C(Cl)=C(Cl)C=CC=1)=O |
| 存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
| 运输: | Room temperature in continental US; may vary elsewhere. |
| 产品描述: | TAS-119 是一种有效的，选择性的，具有口服活性的Aurora A抑制剂，IC50为 1.0 nM。TAS-119 对Aurora A的选择性高于其他蛋白激酶，包括Aurora B(IC50为 95 nM)。TAS-119 具有有效的抗肿瘤活性。 |
| IC50和靶点: | [{name:"Aurora A:1 nM (IC50)"},{name: "Aurora B:95 nM (IC50)"}] |
| In Vitro: | |
| In Vivo: | |
| Clinical Trial: | |
| Solvent & Solubility: |
