FK614
Cat. No.：YN290854
| 产品名称: | FK614 |
| CAS No.: | 193012-35-0 |
| Chemical Name: | 1-[(2,4-Dichlorophenyl)methyl]-2-methyl-N-(pentylsulfonyl)-1H-benzimidazole-6-carboxamide; 1-(2,4-Dichlorobenzyl)-2-Methyl-6-(1-Pentanesulfonylcarbamoyl)Benzimidazole; |
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| 分子量: | 468.40 |
| 分子式: | C21H23Cl2N3O3S |
| SMILES: | O=C(C1=CC=C2N=C(C)N(CC3=CC=C(Cl)C=C3Cl)C2=C1)NS(=O)(CCCCC)=O |
| 存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
| 运输: | Room temperature in continental US; may vary elsewhere. |
| 产品描述: | FK614 是一种口服活性非噻唑烷二酮 (TZD) 型选择性PPARγ调节剂(SPPARM)。FK614 是一种PPARγ激动剂，显示出强大的抗糖尿病活性。FK614 在脂肪细胞分化的各个阶段对PPARγ的激活有不同的影响。FK614 可用于研究高血糖、高甘油三酯血症、糖耐量异常和 2 型糖尿病。 |
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Taygerly, J. P., et al.: Med. Chem. Rev., 51, 53 (2016)
Minoura, H., et al.: Diabetes Obes. Metabo., 9, 369 (2007)
