1-Decarboxy-3-oxo-ceanothic acid
Cat. No.：YN290855
| 产品名称: | 1-Decarboxy-3-oxo-ceanothic acid |
| CAS No.: | 200933-27-3 |
| Chemical Name: | (2E)-2-[(3-Amino-2-pyridinyl)methylene]-hydrazinecarbothioamide; (E)--2-[(3-Amino-2-pyridinyl)methylene]-hydrazinecarbothioamide |
| Synonyms: | 3-AP |
| 分子量: | 195.24 |
| 分子式: | C7H9N5S |
| SMILES: | C1=CC(=C(N=C1)C=NNC(=S)N)N |
| 存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
| 运输: | Room temperature in continental US; may vary elsewhere. |
| 产品描述: | (E)-3-AP 是 3-AP 的E 构型。3-AP 是一种有效的核糖核苷酸还原酶抑制剂。3-AP 显示出抗增殖活性。3-AP 在 L1210 白血病模型中显示出抗癌活性。3-AP 抑制 RR 活性和 DNA 合成。 |
| IC50和靶点: | |
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| Solvent & Solubility: |
Li, J., et al.: Tetrahedron, 54, 393 (1998)
Finch, R.A., et al.: Biochem. Pharmacol., 59, 983 (2000)
