Estramustine
Cat. No.：YN290863
| 产品名称: | Estramustine |
| CAS No.: | 2998-57-4 |
| Chemical Name: | bis(2-Chloroethyl)carbamic Acid 17β-Hydroxyestra-1,3,5(10)-trien-3-yl Ester; 17β-Estradiol 3-[bis(2-chloroethyl)carbamate]; Estracty; Estramustine; Leo 275; NSC 89201; Ro 22-2296/000 |
| Synonyms: | |
| 分子量: | 440.41 |
| 分子式: | C23H31Cl2NO3 |
| SMILES: | 暂无 |
| 存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
| 运输: | Room temperature in continental US; may vary elsewhere. |
| 产品描述: | Estramustine 是一种抗肿瘤剂。Estramustine 通过与微管蛋白 1 (tubulin 1)结合来解聚微管，具有抗有丝分裂活性，对 DU 145 细胞有丝分裂的IC50大约为 16 μM。Estramustine 在前列腺肿瘤异种移植模型中阻断前列腺肿瘤细胞有丝分裂。 |
| IC50和靶点: | |
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| Clinical Trial: | |
| Solvent & Solubility: |
Hilavac, V. et al.: Pharmacogenom., 14, 515 (2013)
