Givinostat
Cat. No.:YN290866
产品名称: | Givinostat |
CAS No.: | 497833-27-9 |
Chemical Name: | |
Synonyms: | ITF-2357 |
分子量: | 暂无 |
分子式: | 暂无 |
SMILES: | 暂无 |
存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
运输: | Room temperature in continental US; may vary elsewhere. |
产品描述: | Givinostat (ITF-2357) 是HDAC抑制剂。抑制HDAC1和HDAC3,IC50分别为 198 nM 和 157 nM。 |
IC50和靶点: | [{name:"hHDAC3:157 nM (IC50)"},{name: "hHDAC1:198 nM (IC50)"},{name: "hHDAC11:292 nM (IC50)"},{name: "hHDAC6:315 nM (IC50)"},{name: "hHDAC2:325 nM (IC50)"},{name: "hHDAC10:340 nM (IC50)"},{name: "hHDAC7:524 nM (IC50)"},{name: "hHDAC5:532 nM (IC50)"},{name: "hHDAC9:541 nM (IC50)"},{name: "hHDAC8:854 nM (IC50)"},{name: "hHDAC4:1059 nM (IC50)"},{name: "HD1-B:7.5 nM (IC50)"},{name: "HD1-A:16 nM (IC50)"},{name: "HD2:10 nM (IC50)"}] |
In Vitro: | |
In Vivo: | |
Clinical Trial: | |
Solvent & Solubility: |