HQ461
Cat. No.:YN290905
CAS No. :1226443-41-9
产品名称: | HQ461 |
CAS No.: | 1226443-41-9 |
Chemical Name: | |
Synonyms: | |
分子量: | 345.44 |
分子式: | C15H15N5OS2 |
SMILES: | 暂无 |
存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
运输: | Room temperature in continental US; may vary elsewhere. |
产品描述: | HQ461 是一种分子胶 (molecular glue),可促进 CDK12-DDB1 相互作用以触发cyclin K降解。 HQ461 介导的 cyclin K 降解损害CDK12功能,导致CDK12底物磷酸化降低、DNA 损伤反应基因下调和细胞死亡。 |
IC50和靶点: | |
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Clinical Trial: | |
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