PERK-IN-4
Cat. No.：YN290906
CAS No. ：1337531-89-1
| 产品名称: | PERK-IN-4 |
| CAS No.: | 1337531-89-1 |
| Chemical Name: | 1-[5-(4-Amino-7-methyl-7H-pyrrolo[2,3-d]pyrimidin-5-yl)-2,3-dihydro-1H-indol-1-yl]-2-[3-fluoro-5-(trifluoromethyl)phenyl]ethanone; 3-Fluoro-GSK2606414 |
| Synonyms: | |
| 分子量: | 469.43 |
| 分子式: | C24H19F4N5O |
| SMILES: | 暂无 |
| 存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
| 运输: | Room temperature in continental US; may vary elsewhere. |
| 产品描述: | PERK-IN-4 是一种有效的选择性PERK抑制剂，IC50值为 0.3 nM。PERK响应与多种疾病状态有关的内质网应激而被激活。 |
| IC50和靶点: | |
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| In Vivo: | |
| Clinical Trial: | |
| Solvent & Solubility: |
Baltzis, D. et al.: J. Biol. Chem., 282, 31675 (2007)
Axten, J. M.et al,: J. Med. Chem. 55(16) 7193 (2012).
