MPT0G211
Cat. No.：YN290917
CAS No. ：2151853-97-1
| 产品名称: | MPT0G211 |
| CAS No.: | 2151853-97-1 |
| Chemical Name: | |
| Synonyms: | |
| 分子量: | 293.326 |
| 分子式: | C17H15N3O2 |
| SMILES: | C(NO)(=O)C1=CC=C(CNC2=C3C(=CC=C2)C=CC=N3)C=C1 |
| 存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
| 运输: | Room temperature in continental US; may vary elsewhere. |
| 产品描述: | MPT0G211 是一种高效、口服活性和选择性的HDAC6抑制剂 (IC50=0.291 nM)。MPT0G211 对HDAC6的选择性是其他HDAC亚型的 1000 倍。MPT0G211 可以透过血脑屏障。MPT0G211 改善阿尔茨海默病模型中 tau 磷酸化和认知缺陷。MPT0G211 具有抗转移和神经保护作用。抗癌活性。 |
| IC50和靶点: | [{name:"HDAC6:0.291 μM (IC50)"}] |
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| In Vivo: | |
| Clinical Trial: | |
| Solvent & Solubility: |
