EHT 5372
Cat. No.：YN290924
CAS No. ：1425945-63-6
| 产品名称: | EHT 5372 |
| CAS No.: | 1425945-63-6 |
| Chemical Name: | |
| Synonyms: | EHT 5372,EHT-5372,EHT5372 |
| 分子量: | 403 |
| 分子式: | C17H11Cl2N5Os |
| SMILES: | N=C(C(S1)=NC2=C1C3=C(NC4=CC=C(Cl)C=C4Cl)N=CN=C3C=C2)OC |
| 存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
| 运输: | Room temperature in continental US; may vary elsewhere. |
| 产品描述: | EHT 5372 是一种高效和选择性的DYRK's家族激酶抑制剂，对DYRK1A，DYRK1B，DYRK2，DYRK3，CLK1，CLK2，CLK4，GSK-3α，和GSK-3β的IC50值分别为 0.22，0.28，10.8，93.2，22.8，88.8，59.0，7.44 和 221 nM。 |
| IC50和靶点: | [{name:"DYRK1A:0.22 nM (IC50)"},{name: "DYRK1B:0.28 nM (IC50)"},{name: "DYRK2:10.8 nM (IC50)"},{name: "DYRK4:93.2 nM (IC50)"},{name: "CLK1:22.8 nM (IC50)"},{name: "CLK2:88.8 nM (IC50)"},{name: "CLK4:59.0 nM (IC50)"},{name: "GSK-3α:7.44 nM (IC50)"},{name: "GSK-3β:221 nM (IC50)"}] |
| In Vitro: | |
| In Vivo: | |
| Clinical Trial: | |
| Solvent & Solubility: |
