PR-104A
Cat. No.:YN290926
CAS No. :680199-06-8
产品名称: | PR-104A |
CAS No.: | 680199-06-8 |
Chemical Name: | |
Synonyms: | SN 27858 |
分子量: | 499.29 |
分子式: | C14H19BrN4O9S |
SMILES: | BrCCN(CCOS(=O)(C)=O)C1=C(C(NCCO)=O)C=C([N+]([O-])=O)C=C1[N+]([O-])=O |
存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
运输: | Room temperature in continental US; may vary elsewhere. |
产品描述: | PR-104A (SN 27858) 是磷酸盐前体 PR-104 的醇代谢物。PR-104A 是一种缺氧选择性的 DNA 交联剂/DNA 损伤剂,也是一种细胞毒素。具有抗肿瘤活性。PR-104A 在缺氧条件下通过 1-电子 NADPH:细胞色素 P450 氧化还原酶代谢。可用于复发/难治性 T 系急性淋巴细胞白血病 (T-ALL) 的研究。 |
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