PF-3758309 hydrochloride
Cat. No.：YN290941
| 产品名称: | PF-3758309 hydrochloride |
| CAS No.: | 1279034-84-2 |
| Chemical Name: | |
| Synonyms: | PF-03758309 hydrochloride |
| 分子量: | 527.09 |
| 分子式: | C25H31ClN8OS |
| SMILES: | 暂无 |
| 存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
| 运输: | Room temperature in continental US; may vary elsewhere. |
| 产品描述: | PF-3758309 (PF-03758309) hydrochloride 是一种有效的、口服的、可逆的 ATP 竞争性PAK4抑制剂 (Kd= 2.7 nM;Ki=18.7 nM)。PF-3758309 hydrochloride 具有PAK4抑制剂的预期细胞功能：抑制锚定独立生长、诱导凋亡、细胞骨架重塑和抑制增殖。 |
| IC50和靶点: | [{name:"PAK4:18.7 nM (Ki)"},{name: "PAK1:13.7 nM (Ki)"},{name: "PAK5:18.1 nM (Ki)"},{name: "PAK6:17.1 nM (Ki)"},{name: "PAK2:190 nM (IC50)"},{name: "PAK3:99 nM (IC50)"},{name: "PAK4:2.7 nM (Kd)"}] |
| In Vitro: | |
| In Vivo: | |
| Clinical Trial: | |
| Solvent & Solubility: |
