Tubulin inhibitor 18
Cat. No.：YN290955
| 产品名称: | Tubulin inhibitor 18 |
| CAS No.: | 159776-69-9 |
| Chemical Name: | N,N-Dimethyl-L-valyl-L-valyl-N-methyl-L-valyl-L-prolyl-N-(phenylmethyl)-L-prolinamide; LU 103793 |
| Synonyms: | 西马多丁; LU103793 free base |
| 分子量: | 640.86 |
| 分子式: | C35H56N6O5 |
| SMILES: | 暂无 |
| 存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
| 运输: | Room temperature in continental US; may vary elsewhere. |
| 产品描述: | Cemadotin (LU103793) 是Dolastatin 15(HY-P1126) 的类似物，Dolastatin 15 是天然存在的细胞毒性肽。Cemadotin 阻止细胞有丝分裂，抑制微管 (tubulin) 的Ki为 1 μM。Cemadotin 可用于抗癌研究。 |
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Jordan, M., et al.: Biochemistry, 37, 17571 (1998)
Mross, K., et al.: Onkologie, 19, 490 (1996)
Supko, J.G., et al.: Cancer Chemoth. Pharm., 46, 319 (2000)
