JAK 3i
Cat. No.：YN310576
| 产品名称: | JAK 3i |
| CAS No.: | 1918238-72-8 |
| Chemical Name: | |
| Synonyms: | JAK3 inhibitor JAK3i |
| 分子量: | 354.34 |
| 分子式: | C18H15FN4O3 |
| SMILES: | 暂无 |
| 存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
| 运输: | Room temperature in continental US; may vary elsewhere. |
| 产品描述: | JAK3i 是一种高选择性的JAK3抑制剂 (IC50: 0.43 nM)。JAK3i 与JAK3中的半胱氨酸形成共价键，但不与 JAK1、JAK2 或TYK2中密切相关的激酶结构域形成共价键。JAK3i 在体内抑制IL-2驱动的 t 细胞增殖，具有自身免疫性疾病研究的潜力。 |
| IC50和靶点: | [{name:"JAK3:0.43 nM (IC50)"},{name: "JAK2:8680 nM (IC50)"},{name: "JAK1:1520 nM (IC50)"}] |
| In Vitro: | |
| In Vivo: | |
| Clinical Trial: | |
| Solvent & Solubility: |
