AAPK-25
Cat. No.：YN290975
CAS No. ：2247919-28-2
| 产品名称: | AAPK-25 |
| CAS No.: | 2247919-28-2 |
| Chemical Name: | |
| Synonyms: | |
| 分子量: | 442.32 |
| 分子式: | C21H13Cl2N3O2S |
| SMILES: | 暂无 |
| 存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
| 运输: | Room temperature in continental US; may vary elsewhere. |
| 产品描述: | AAPK-25 是一种有效选择性的Aurora/PLK激酶双重抑制剂，具有抗肿瘤活性。AAPK-25 可引起有丝分裂延迟并阻滞前中期细胞，通过生物标志物组蛋白 H3Ser10磷酸化反应，随后细胞凋亡激增。AAPK-25 靶向 Aurora-A, -B, -C 的Kd值为 23 nM-289 nM，靶向 PLK-1, -2, -3 的Kd值为 55-456 nM。 |
| IC50和靶点: | |
| In Vitro: | |
| In Vivo: | |
| Clinical Trial: | |
| Solvent & Solubility: |
