IRE1α kinase-IN-1
Cat. No.：YN290981
| 产品名称: | IRE1α kinase-IN-1 |
| CAS No.: | 2328097-41-0 |
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| 分子量: | 504.99 |
| 分子式: | C26H26ClFN8 |
| SMILES: | 暂无 |
| 存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
| 运输: | Room temperature in continental US; may vary elsewhere. |
| 产品描述: | IRE1α kinase-IN-1 是一种高度选择性的IRE1α (ERN1)抑制剂，IC50为 77 nM。IRE1α kinase-IN-1 对 IRE1α 的选择性比 IRE1β 亚型高 100 倍。IRE1α kinase-IN-1 抑制内质网诱导的 IRE1α 寡聚和自磷酸化，并抑制 IRE1α RNase 活性 (IC50=80 nM)。 |
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