SR-0813
Cat. No.：YN310592
| 产品名称: | SR-0813 |
| CAS No.: | 2597186-19-9 |
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| 分子量: | 496.62 |
| 分子式: | C25H32N6O3S |
| SMILES: | 暂无 |
| 存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
| 运输: | Room temperature in continental US; may vary elsewhere. |
| 产品描述: | SR-0813 是一种有效的选择性ENL/AF9 YEATS结构域抑制剂。SR-0813 对于 ENL YEATS 结构域的IC50和EC50值分别为 25 nM 和 205 nM。SR-0813 对于 AF9 YEATS 结构域的IC50和EC50值分别为 311 nM 和 76 nM (CETSA)。SR-0813 结合MAP3K19的亲和力 (Kd=3.5 μM) 比 ENL YEATS (Kd=30 nM) 低 100 倍以上。SR-0813 可用于急性白血病的研究。 |
| IC50和靶点: | [{name:"ENL YEATS domain:25 nM (IC50)"},{name: "ENL YEATS domain:205 nM (EC50)"},{name: "AF9 YEATS domain:311 nM (IC50)"},{name: "AF9 YEATS domain:76 nM (EC50)"},{name: "ENL YEATS domain:30 nM (Kd)"},{name: "MAP3K19:3.5 μM (Kd)"}] |
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