Decitabine
Cat. No.：YN270411
CAS No. ：2353-33-5
| 产品名称: | Decitabine |
| CAS No.: | 2353-33-5 |
| Chemical Name: | 4-amino-1-(2-deoxy-β-D-erythro-pentofuranosyl)-1,3,5-triazin-2(1H)-one |
| Synonyms: | 地西他滨; 5-Aza-2'-deoxycytidine; 5-AZA-CdR; NSC 127716 |
| 分子量: | 228.21 |
| 分子式: | C₈H₁₂N₄O₄ |
| SMILES: | O=C1N=C(N)N=CN1[C@H](O[C@@H]2CO)C[C@@H]2O |
| 存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
| 运输: | Room temperature in continental US; may vary elsewhere. |
| 产品描述: | Decitabine (5-Aza-2'-deoxycytidine) 是一种具有口服活性的脱氧胞苷类似物抗代谢物 (deoxycytidine analogue antimetabolite) 和 DNA 甲基转移酶 (DNA methyltransferase) 抑制剂。Decitabine 代替 DNA 掺入胞嘧啶可以将 DNA 甲基转移酶共价捕获到 DNA 中，从而导致对该酶的不可逆抑制。Decitabine 诱导细胞 G2/M 阻滞和细胞凋亡 (apoptosis)。Decitabine 具有有 |
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