STF-62247
Cat. No.:YN280006
CAS No. :315702-99-9
产品名称: | STF-62247 |
CAS No.: | 315702-99-9 |
Chemical Name: | N-(3-methylphenyl)-4-(4-pyridinyl)-2-thiazolamine |
Synonyms: | STF 62247 |
分子量: | 267.35 |
分子式: | C₁₅H₁₃N₃S |
SMILES: | CC1=CC(NC2=NC(C3=CC=NC=C3)=CS2)=CC=C1 |
存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
运输: | Room temperature in continental US; may vary elsewhere. |
产品描述: | STF-62247是一个TGN抑制剂,在RCC4 和RCC4/VHL细胞中的IC50分别是0.625 μM和16 μM。 |
IC50和靶点: | |
In Vitro: | |
In Vivo: | |
Clinical Trial: | |
Solvent & Solubility: |
Turcotte, S., Sutphin, P.D., and Giaccia, A.J.Targeting therapy for the loss of von Hippel-Lindau in renal cell carcinoma a novel molecule that induces autophagic cell deathAutophagy4(7),944-946(2008)
Turcotte, S., Chan, D.A., Sutphin, P.D., et al.A molecule targeting VHL-deficient renal cell carcinoma that induces autophagyCancer Cell14(1),90-102(2008)
Chan, D.A., and Giaccia, A.J.Targeting cancer cells by synthetic lethality autophagy and VHL in cancer therapeuticsCell Cycle7(19),2987-2990(2008)