JPH203
Cat. No.：YN280007
CAS No. ：1037592-40-7
| 产品名称: | JPH203 |
| CAS No.: | 1037592-40-7 |
| Chemical Name: | O-[(5-amino-2-phenyl-7-benzoxazolyl)methyl]-3,5-dichloro-L-tyrosine |
| Synonyms: | KYT-0353 |
| 分子量: | 472.32 |
| 分子式: | C₂₃H₁₉Cl₂N₃O₄ |
| SMILES: | N[C@@H](CC1=CC(Cl)=C(C(Cl)=C1)OCC2=C(OC(C3=CC=CC=C3)=N4)C4=CC(N)=C2)C(O)=O |
| 存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
| 运输: | Room temperature in continental US; may vary elsewhere. |
| 产品描述: | JPH203 (KYT-0353) 是有效，选择性的 L 型氨基酸转运蛋白 1 (LAT-1) 抑制剂。JPH203 具有抗癌活性。 |
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Oda, K., Hosoda, N., Endo, H., et al.L-type amino acid transporter 1 inhibitors inhibit tumor cell growthCancer Sci.101(1),173-179(2010)
Yun, D.-W., Lee, S.A., Park, M.-G., et al.JPH203, an L-type amino acid transporter 1–selective compound, induces apoptosis of YD-38 human oral cancer cellsJ. Pharmacol. Sci.124(2),208-217(2014)
