Veliparib
Cat. No.:YN280008
CAS No. :912444-00-9
产品名称: | Veliparib |
CAS No.: | 912444-00-9 |
Chemical Name: | 2-[(2R)-2-Methyl-2-pyrrolidinyl]-1H-benzimidazole-7-carboxamide; A 861695; |
Synonyms: | 维利帕尼; ABT-888 |
分子量: | 244.29 |
分子式: | C₁₃H₁₆N₄O |
SMILES: | O=C(C1=C2NC([C@@]3(NCCC3)C)=NC2=CC=C1)N |
存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
运输: | Room temperature in continental US; may vary elsewhere. |
产品描述: | Veliparib (ABT-888) 是一种有效的PARP抑制剂,抑制PARP1和PARP2的Ki分别为 5.2 和 2.9 nM。 |
IC50和靶点: | [{name:"PARP-2:2.9 nM (Ki)"},{name: "PARP-1:5.2 nM (Ki)'}, 'Autophagy'] |
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In Vivo: | |
Clinical Trial: | |
Solvent & Solubility: |
Virag, L., et al.: Pharmacol. Rev., 54, 375