GW 501516
Cat. No.:YN280022
CAS No. :317318-70-0
产品名称: | GW 501516 |
CAS No.: | 317318-70-0 |
Chemical Name: | 2-[2-methyl-4-[[[4-methyl-2-[4-(trifluoromethyl)phenyl]-5-thiazolyl]methyl]thio]phenoxy]-acetic acid |
Synonyms: | GW 1516; GSK-516 |
分子量: | 453.50 |
分子式: | C₂₁H₁₈F₃NO₃S₂ |
SMILES: | OC(COC1=CC=C(C=C1C)SCC2=C(N=C(S2)C3=CC=C(C=C3)C(F)(F)F)C)=O |
存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
运输: | Room temperature in continental US; may vary elsewhere. |
产品描述: | GW 501516 (GW 1516) 是PPARδ的激动剂,EC50值为 1.1 nM。 |
IC50和靶点: | [{name:"PPARδ:1.1 nM (EC50)"}] |
In Vitro: | |
In Vivo: | |
Clinical Trial: | |
Solvent & Solubility: |
Thevis, M., Möller, I., Thomas, A., et al.Characterization of two major urinary metabolites of the PPARδ-agonist GW1516 and implementation of the drug in routine doping controlsAnal. Bioanal. Chem.396(7),2479-2491(2010)