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GW 501516

Cat. No.:YN280022

  • CAS No. :317318-70-0

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    • 参考文献
    • 产品名称: GW 501516
      CAS No.: 317318-70-0
      Chemical Name: 2-[2-methyl-4-[[[4-methyl-2-[4-(trifluoromethyl)phenyl]-5-thiazolyl]methyl]thio]phenoxy]-acetic acid
      Synonyms:GW 1516; GSK-516
      分子量:453.50
      分子式:C₂₁H₁₈F₃NO₃S₂
      SMILES:OC(COC1=CC=C(C=C1C)SCC2=C(N=C(S2)C3=CC=C(C=C3)C(F)(F)F)C)=O
      存储:Please store the product under the recommended conditions in theCertificate of Analysis.
      运输:Room temperature in continental US; may vary elsewhere.
      Select Batch:
      Purity: 98%
    • 产品描述: GW 501516 (GW 1516) 是PPARδ的激动剂,EC50值为 1.1 nM。
      IC50和靶点: [{name:"PPARδ:1.1 nM (EC50)"}]
      In Vitro:
      In Vivo:
      Clinical Trial:
      Solvent & Solubility:
    • Thevis, M., Möller, I., Thomas, A., et al.Characterization of two major urinary metabolites of the PPARδ-agonist GW1516 and implementation of the drug in routine doping controlsAnal. Bioanal. Chem.396(7),2479-2491(2010)

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