GW406108X
Cat. No.:YN280029
CAS No. :1644443-92-4
产品名称: | GW406108X |
CAS No.: | 1644443-92-4 |
Chemical Name: | |
Synonyms: | GW108X |
分子量: | 400.21 |
分子式: | C₂₀H₁₁Cl₂NO₄ |
SMILES: | O=C1NC2=C(C=C(C(C3=CC=CO3)=O)C=C2)/C1=C/C4=CC(Cl)=C(O)C(Cl)=C4 |
存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
运输: | Room temperature in continental US; may vary elsewhere. |
产品描述: | GW406108X 是特异性的Kif15 (Kinesin-12)抑制剂,IC50为 0.82 uM。GW406108X 是一种有效的自噬 (autophagy) 抑制剂, ATP 竞争性抑制ULK1,pIC50为 6.37 (427 nM)。GW406108X 抑制 ULK1 和自噬,而不影响 mTOR 或 AMPK 活性。 |
IC50和靶点: | |
In Vitro: | |
In Vivo: | |
Clinical Trial: | |
Solvent & Solubility: |