Vinorelbine ditartrate
Cat. No.:YN280034
CAS No. :125317-39-7
产品名称: | Vinorelbine ditartrate |
CAS No.: | 125317-39-7 |
Chemical Name: | (2β,3β,4β,5α,12R,19α)-4-(acetyloxy)-6,7-didehydro-15-[(2R,6R,8S)-4-ethyl-1,3,6,7,8,9-hexahydro-8-(methoxycarbonyl)-2,6-methano-2H-azecino[4,3-b]indol-8-yl]-3-hydroxy-16-methoxy-1-methyl-aspidospermidine-3-carboxylic acid, methyl ester, 2R,3R-dihydroxybuta |
Synonyms: | 酒石酸长春瑞滨; KW-2307; Nor-5'-anhydrovinblastine ditartrate |
分子量: | 1079.11 |
分子式: | C₅₃H₆₆N₄O₂₀ |
SMILES: | CC[C@@]1(C=CCN2CC3)[C@@]2([H])[C@@]3(C(C=C([C@@](C4=C5C(C=CC=C6)=C6N4)(CC(C=C(CC)C7)([H])CN7C5)C(OC)=O)C(OC)=C8)=C8N9C)[C@]9([H])[C@](C(OC)=O)(O)[C@@H]1OC(C)=O.O=C(O)[C@H](O)[C@@H](O)C(O)=O.O=C(O)[C@H](O)[C@@H](O)C(O)=O |
存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
运输: | Room temperature in continental US; may vary elsewhere. |
产品描述: | Vinorelbine ditartrate 是一种抗有丝分裂剂,能够抑制 Hela 细胞的增殖,IC50值为 1.25 nM。 |
IC50和靶点: | |
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Ngan, V.K., Bellman, K., Hill, B.T., et al.Mechanism of mitotic block and inhibition of cell proliferation by the semisynthetic Vinca alkaloids vinorelbine and its newer derivative vinflunineMol. Pharmacol.60(1),225-232(2001)