AC-73
Cat. No.:YN280037
CAS No. :775294-71-8
产品名称: | AC-73 |
CAS No.: | 775294-71-8 |
Chemical Name: | |
Synonyms: | AC 73;AC73 |
分子量: | 319.40 |
分子式: | C₂₁H₂₁NO₂ |
SMILES: | OC(CNCC1=CC=C(C2=CC=CC=C2)C=C1)C3=CC=CC(O)=C3 |
存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
运输: | Room temperature in continental US; may vary elsewhere. |
产品描述: | AC-73 是Cluster of Differentiation 147 (CD147)的第一种特定的口服生物利用的抑制剂,可特异性破坏CD147的二聚化 (结合位点在CD147的 N 端 IgC2 域中包括 Glu64 和 Glu73),从而抑制CD147/ERK1/2/STAT3/MMP-2 途径,并抑制肝癌细胞的运动和侵袭。AC-73 还是一种抗增殖药,也是白血病细胞自噬的诱导剂。 |
IC50和靶点: | |
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