Bromocriptine mesylate
Cat. No.：YN280047
CAS No. ：22260-51-1
| 产品名称: | Bromocriptine mesylate |
| CAS No.: | 22260-51-1 |
| Chemical Name: | (5α)-2-bromo-12'-hydroxy-2'-(1-methylethyl)-5'-(2-methylpropyl)-errgotaman-3',6',18-trione, monomethanesulfonate |
| Synonyms: | 甲磺酸溴隐亭; CB-154 |
| 分子量: | 750.70 |
| 分子式: | C₃₃H₄₄BrN₅O₈S |
| SMILES: | [H][C@@]12CC3=C(Br)NC4=CC=CC(C1=C[C@@H](C(N[C@@]5(C(C)C)C(N6[C@@H](CC(C)C)C(N7CCC[C@]7([C@]6(O)O5)[H])=O)=O)=O)CN2C)=C43.OS(=O)(C)=O |
| 存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
| 运输: | Room temperature in continental US; may vary elsewhere. |
| 产品描述: | Bromocriptine mesylate 是一种有效的多巴胺D2/D3受体激动剂，结合多巴胺 D2 受体，pKi为 8.05±0.2。 |
| IC50和靶点: | |
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| Solvent & Solubility: |
Kvernmo, T., Härtter, S., and Bürger, E.A review of the receptor-binding and pharmacokinetic properties of dopamine agonistsClin. Ther.28(8),1065-1078(2006)
Millan, M.J., Maiofiss, L., Cussac, D., et al.Differential actions of antiparkinson agents at multiple classes of monoaminergic receptor. I. A multivariate analysis of the binding profiles of 14 drugs at 21 native and cloned human receptor subtypesJ. Pharmacol. Exp. Ther.303(2),791-804(2002)
Rouillard, C., Bédard, P.J., and De Paolo, T.Effects of chronic treatment of MPTP monkeys with bromocriptine alone or in combination with SKF 38393Eur. J. Pharmacol.185(2-3),209-215(1990)
