LC3-mHTT-IN-AN2
Cat. No.：YN280053
| 产品名称: | LC3-mHTT-IN-AN2 |
| CAS No.: | 7758-73-8 |
| Chemical Name: | |
| Synonyms: | 5,7-Dihydroxy-4-phenylcoumarin,5,7-二羟基-4-苯基香豆素 |
| 分子量: | 254.24 |
| 分子式: | C₁₅H₁₀O₄ |
| SMILES: | OC1=C2C(OC(C=C2C3=CC=CC=C3)=O)=CC(O)=C1 |
| 存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
| 运输: | Room temperature in continental US; may vary elsewhere. |
| 产品描述: | LC3-mHTT-IN-AN2 (Compound AN2) 是一种mHTT-LC3连接化合物，LC3-mHTT-IN-AN2 与突变型亨廷顿蛋白 (mHTT) 和 LC3B 相互作用，但不与 wtHTT 或无关的对照蛋白相互作用。LC3-mHTT-IN-AN2 以等位基因选择性的方式降低了亨廷顿病 (HD) 小鼠神经元中mHTT水平。 |
| IC50和靶点: | |
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