THZ-P1-2
Cat. No.：YN280065
CAS No. ：2058075-45-7
| 产品名称: | THZ-P1-2 |
| CAS No.: | 2058075-45-7 |
| Chemical Name: | |
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| 分子量: | 531.61 |
| 分子式: | C₃₁H₂₉N₇O₂ |
| SMILES: | O=C(C(C=C1)=CC=C1NC(/C=C/CN(C)C)=O)NC2=CC=CC(NC3=CC(C4=CNC5=CC=CC=C45)=NC=N3)=C2 |
| 存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
| 运输: | Room temperature in continental US; may vary elsewhere. |
| 产品描述: | THZ-P1-2 是一种首创的，选择性的PI5P4K抑制剂，对 PI5P4Kα 的IC50为 190 nM。THZ-P1-2 共价靶向 PI5P4Kα/β/γ 中无序环上的半胱氨酸。THZ-P1-2 引起自噬破坏，上调 TFEB 信号传导。THZ-P1-2 在白血病细胞系中显示抗癌活性。 |
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