Topotecan
Cat. No.：YN280066
CAS No. ：123948-87-8
| 产品名称: | Topotecan |
| CAS No.: | 123948-87-8 |
| Chemical Name: | (S)-10-[(Dimethylamino)methyl]-4-ethyl-4,9-dihydroxy-1H-pyrano[3',4':6,7]indolizino[1,2-b]quinoline-3,14(4H,12H)-dione; Topotecan; 10-Hydroxy-9-[(dimethylamino)methyl]-(20S)-camptothecin; 9-(N,N-Dimethylaminomethyl)-10-hydroxycamptothecin; Hycamptamine; H |
| Synonyms: | 拓扑替康; SKF 104864A; NSC 609669 |
| 分子量: | 421.45 |
| 分子式: | C₂₃H₂₃N₃O₅ |
| SMILES: | O=C1[C@](O)(CC)C2=C(CO1)C(N3CC4=CC5=C(CN(C)C)C(O)=CC=C5N=C4C3=C2)=O |
| 存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
| 运输: | Room temperature in continental US; may vary elsewhere. |
| 产品描述: | Topotecan (SKF 104864A; NSC 609669) 是拓扑异构酶I抑制剂。 |
| IC50和靶点: | |
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| Clinical Trial: | |
| Solvent & Solubility: |
Beijnen, J.H., et al.: J. Pharm. Biomed. Anal., 8, 789 (1990)
BeiKingsburg, W.D., et al.: J. Med. Chem., 34, 98 (1991)
Rowinsky, E.K., et al.: J. Clin. Oncol., 10, 647 (1992)
