Zoledronic acid monohydrate
Cat. No.：YN280068
| 产品名称: | Zoledronic acid monohydrate |
| CAS No.: | 165800-06-6 |
| Chemical Name: | P,P'-[1-hydroxy-2-(1H-imidazol-1-yl)ethylidene]bis-phosphonic acid, monohydrate |
| Synonyms: | 唑来膦酸一水合物; Zoledronate monohydrate; CGP 42446 monohydrate; CGP42446A monohydrate; ZOL 446 monohydrate |
| 分子量: | 290.10 |
| 分子式: | C₅H₁₂N₂O₈P₂ |
| SMILES: | OC(P(O)(O)=O)(P(O)(O)=O)CN1C=CN=C1.[H]O[H] |
| 存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
| 运输: | Room temperature in continental US; may vary elsewhere. |
| 产品描述: | Zoledronic acid monohydrate 是第三代含氮二磷酸盐，能够抑制破骨细胞介导的骨吸收，同时具有抗肿瘤的活性。 |
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Räkel, A., Boucher, A., and Ste-Marie, L.G.Role of zoledronic acid in the prevention and treatment of osteoporosisClin. Interv. Aging6,89-99(2011)
El-Amm, J., Freeman, A., Patel, N., et al.Bone-targeted therapies in metastatic castration-resistant prostate cancer: Evolving paradigmsProstate Cancer2013,1-10(2013)
Major, P.The use of zoledronic acid, a novel, highly potent bisphosphonate, for the treatment of hypercalcemia of malignancyOncologist7(6),481-491(2002)
Michou, L., and Brown, J.P.Emerging strategies and therapies for treatment of Paget's disease of boneDrug Des. Devel. Ther.5,225-239(2011)
