Carboplatin
Cat. No.：YN280100
| 产品名称: | Carboplatin |
| CAS No.: | 41575-94-4 |
| Chemical Name: | (SP-4-2)-diammine[1,1-cyclobutanedicarboxylato(2-)-κO,κO'']-platinum |
| Synonyms: | 卡铂; NSC 241240 |
| 分子量: | 371.25 |
| 分子式: | C₆H₁₂N₂O₄Pt |
| SMILES: | O=C1C2(CCC2)C(O[Pt]O1)=O.N.N |
| 存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
| 运输: | Room temperature in continental US; may vary elsewhere. |
| 产品描述: | Carboplatin (NSC 241240) 是一种DNA 合成抑制剂，其与 DNA 结合，抑制复制和转录并诱导细胞死亡。Carboplatin (NSC 241240) 是顺铂的衍生物，是一种有效的抗癌剂。 |
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Micetich, K.C., Barnes, D., and Erickson, L.C.A comparative study of the cytotoxicity and DNA-damaging effects of cis-(diammino)(1,1-cyclobutanedicarboxylato)-platinum(II) and cis-diamminedichloroplatinum(II) on L1210 cellsCancer Res.45(9),4043-4047(1985)
Groen, H.J., Sleijfer, S., Meijer, C., et al.Carboplatin- and cisplatin-induced potentiation of moderate-dose radiation cytotoxicity in human lung cancer cell linesBr. J. Cancer72(6),1406-1411(1995)
Al-Eisawi, Z., Beale, P., Chan, C., et al.Carboplatin and oxaliplatin in sequenced combination with bortezomib in ovarian tumour modelsJ. Ovarian Res.6(1),78(2013)
Kelland, L.R., Abel, G., McKeage, M.J., et al.Preclinical antitumor evaluation of bis-acetato-ammine-dichloro-cyclohexylamine platinum(IV): An orally active platinum drugCancer Res.53(11),2581-2586(1993)
