Trimetazidine
Cat. No.：YN280117
| 产品名称: | Trimetazidine |
| CAS No.: | 5011-34-7 |
| Chemical Name: | 1-[(2,3,4-Trimethoxyphenyl)methyl]piperazine; 4-(2,3,4-Trimethoxybenzyl)piperazine; Preductal; Preductal MB; TMZ; Trimetazidine; Trimetazidine (TMZ); Vasorel; |
| Synonyms: | |
| 分子量: | 266.34 |
| 分子式: | C₁₄H₂₂N₂O₃ |
| SMILES: | COC1=CC=C(CN2CCNCC2)C(OC)=C1OC |
| 存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
| 运输: | Room temperature in continental US; may vary elsewhere. |
| 产品描述: | Trimetazidine 是一种选择性的长链3-ketoyl coenzyme A thiolase抑制剂，IC50值为 75 nM，可抑制游离脂肪酸的 β-氧化。Trimetazidine 是一种有效的抗心绞痛剂和一种细胞保护剂，具有抗氧化，抗炎，抗伤害和胃保护作用。Trimetazidine 诱导自噬 (autophagy)，还是一种HADHA抑制剂。 |
| IC50和靶点: | |
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| Clinical Trial: | |
| Solvent & Solubility: |
Zhang, D.: Xiandai Zhenduan Yu Zhiliao, 28, 2618 (2017)
