Licochalcone A
Cat. No.：YN280127
CAS No. ：58749-22-7
| 产品名称: | Licochalcone A |
| CAS No.: | 58749-22-7 |
| Chemical Name: | (2E)-3-[5-(1,1-dimethyl-2-propen-1-yl)-4-hydroxy-2-methoxyphenyl]-1-(4-hydroxyphenyl)-2-propen-1-one |
| Synonyms: | Licochalcone-A |
| 分子量: | 338.40 |
| 分子式: | C₂₁H₂₂O₄ |
| SMILES: | O=C(C1=CC=C(O)C=C1)/C=C/C2=CC(C(C)(C)C=C)=C(O)C=C2OC |
| 存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
| 运输: | Room temperature in continental US; may vary elsewhere. |
| 产品描述: | 甘草查尔酮A (Licochalcone A)是一种黄酮类化合物，具有抗癌功效，对UGT1A1的IC50值为0.97 μM。 |
| IC50和靶点: | |
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| Solvent & Solubility: |
Smit, N., Vicanova, J., and Pavel, S.The hunt for natural skin whitening agentsInt. J. Mol. Sci.10(12),5326-5349(2009)
Angelova-Fischer, I., Neufang, G., Jung, K., et al.A randomized, investigator-blinded efficacy assessment study of stand-alone emollient use in mild to moderately severe atopic dermatitis flaresJ. Eur. Acad. Dermatol. Venereol.28(Suppl 3),9-15(2014)
Weber, T.M., Ceilley, R.I., Buerger, A., et al.Skin tolerance, efficacy, and quality of life of patients with red facial skin using a skin care regimen containing Licochalcone AJ. Cosmet. Dermatol.5(3),227-232(2006)
Yuan, X., Li, D., Zhao, H., et al.Licochalcone A-induced human bladder cancer T24 cells apoptosis triggered by mitochondria dysfunction and endoplasmic reticulum stressBiomed Res. Int.2013,1-9(2013)
Tsai, J.P., Hsiao, P.C., Yang, S.F., et al.Licochalcone A suppresses migration and invasion of human hepatocellular carcinoma cells through downregulation of MKK4/JNK via NF-κB mediated urokinase plasminogen activator expressionPLoS One9(1),1-12(2014)
Tsukiyama, R.I., Katsura, H., Tokuriki, N., et al.Antibacterial activity of licochalcone A against spore-forming bacteriaAntimicrob. Agents Chemother.46(5),1226-1230(2002)
Ziegler, H.L., Hansen, H.S., Staerk, D., et al.The antiparasitic compound licochalcone a is a potent echinocytogenic agent that modifies the erythrocyte membrane in the concentration range where antiplasmodial activity is observedAntimicrob. Agents Chemother.48(10),4067-4071(2004)
